I've been taking Hadlima for a year and Hydroxychloroquine for three. My A1C just spiked unexpectedly, even though my finger-prick tests and lab results show normal glucose. What's going on?

The title covers the basics, but here are the details: Two weeks ago, my labs showed an A1C in the pre-diabetic zone, which was a big jump from before. My doctor hasn’t brought it up since it’s just part of the standard metabolic panel. I should also mention I’ve had some minor kidney concerns for the past two years. Looking back at my records, I noticed my A1C has been slowly rising for eight years. I started testing my glucose at home—before meals and at 1, 2, and 3-hour intervals after. My peak was only 135 after dinner; otherwise, I’m usually in the 90s. This doesn’t match an A1C that suggests an average of 135. I even ate a high-sugar breakfast today to find a spike, but I only hit 97. Could my PsA medications be causing inaccurate A1C results? Does anyone know where these supposed massive spikes could be hiding, or is there something else I’m missing? I’m really stumped.

I’m following this thread. I don’t have any solutions, but I’m curious about the responses. My own A1C stays between 5.4 and 5.7.

A brief search suggests there isn’t a proven link between biologics and rising A1C levels. Is there a history of type 2 diabetes or metabolic issues in your family? Additionally, for those with a uterus, things like PCOS or previous gestational diabetes can raise your risk. It’s also frequent for those with one autoimmune condition to develop others, including diabetes. Getting a CGM like the Freestyle Libre for a few weeks is a solid suggestion to see your full glucose patterns.

You might miss the full picture without a continuous monitor. I personally use Abbott’s Lingo. It’s available without a prescription and helps spot trends or specific times when levels spike. Stelo is another option.