I wanted to open up about my experience using LDN to manage my small fiber neuropathy now that I’ve been on it for a solid eight months. Before I began this treatment, I was struggling with severe depression due to constant, 24/7 nerve pain. For those lucky enough to avoid nerve damage, it feels like being relentlessly attacked by hornets. I was in a state of mental exhaustion and desperation. After reading a success story here, I decided to give LDN a chance. The improvement was very gradual, and there were several moments where I almost gave up, but I am so relieved I persisted. I am now largely free of pain. The burning sensations in my legs have vanished, and the deep nerve pain in my toe and chest is gone. Even the constant tingling in my pelvic floor has cleared up. The only thing left is occasional stabbing pain, which happens much less frequently now. Being on LDN gave me the mental space to identify that my diet—specifically gluten and tomatoes—was triggering my symptoms. I’ve actually purchased a two-year supply of the medication just in case tariffs impact availability, as I plan to stay on it until a better alternative exists. I do deal with the side effect of intense dreams, which is difficult with my PTSD, but the daytime relief is worth it. If you’re hesitant, remember that while it doesn’t work for everyone, you won’t know if it helps you until you try. I hope you all find relief for your conditions.
Did you encounter any harsh side effects during the initial period?
This is such a fantastic update, I’m really happy for you. Could you share what your starting dose was and how you went about increasing it? Also, what is your current daily dose?
What a wonderful outcome! Thank you for posting your story. I’m also finding that LDN is helping immensely with my own neuropathy pain.
I also struggled with small fiber neuropathy, which was initially misidentified as fibromyalgia. I had a hard time with the medications I was prescribed, like pregabalin and duloxetine, because they caused hyperalgesia. Changing my diet to keto was actually the most helpful thing for me. I found that processed sugar, nightshades like potatoes and tomatoes, and high-histamine foods were my biggest triggers. I cut out most carbs and now stick to nuts, seeds, berries, eggs, meat, and green veggies. It’s a strict way to live, but it’s better than the two years I spent bedridden in total agony. My condition seemed to be linked to pre-diabetes brought on by chronic stress and long covid. I’ve just started LDN and am in my second week. After a year of dealing with ME/CFS symptoms, I’ve had some good moments on LDN, though I’m currently feeling quite fatigued and sluggish. My dreams were vivid the first night but have since leveled off. I’m taking 2mg right now and plan to work up to 4.5mg, splitting the dose to help with the exhaustion and heavy eyes while managing my PEM.